David J Durgan

David J Durgan, Ph.D.

Assistant Professor

Email

durgan@bcm.edu

Positions

Assistant Professor: Integrative Physiology & Anesthesiology
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Houston, TX, US

Addresses

BCM-315B (Office): Houston, TX, 77030
United States

BCM 307/315B (Lab): Houston, TX, 77030
United States

Education

PhD from University of Alabama at Birmingham: 12/2011 - Birmingham, AL

MS from California Polytechnic State University: 03/2005 - San Luis Obispo, CA

BS from University of Wyoming: 06/2000 - Laramie, WY

Professional Interests

Role of the gut microbiota in cardiovascular disease

Professional Statement

Ongoing research in my laboratory is focused on the role of the gut microbiota in cardiovascular diseases. We are particularly interested in how these bacteria residing in the gut influence host blood pressure. We have shown that disrupting the bacterial population in the gut leads to hypertension, and that various methods to normalize gut bacteria can be therapeutic. Using rodent models, in vitro assay, and muli-omics approaches we are working to understand the mechanisms of communication between the gut microbiota and host that are involved in blood pressure regulation.

Websites

Selected Publications

Shi H, Zhang B, Abo-Hamzy T, Nelson JW, Ambati CSR, Petrosino JF, Bryan RM Jr, Durgan DJ.. " " Circ Res. 2021 ;
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Nelson JW, Phillips SC, Ganesh BP, Petrosino JF, Durgan DJ, Bryan RM. " " FASEB J. 2021 Feb ;
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Durgan DJ, Lee J, McCullough LD, Bryan RM Jr.. " " Stroke. 2019 Aug ;
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Ganesh BP, Nelson JW, Eskew JR, Ganesan A, Ajami NJ, Petrosino JF, Bryan RM Jr, Durgan DJ.. " " Hypertension. 2018 Nov ;
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Durgan DJ. " " Hypertens Rep.. 2017 ;
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Adnan,S.;Nelson,J.W.;Ajami,N.J.;Venna,V.R.;Petrosino,J.F.;Bryan,R.M.,Jr;Durgan,D.J.;. " " Physiol Genomics.. 2016 ;
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Durgan DJ, Ganesh BP, Cope JL, Ajami NJ, Phillips SC, Petrosino JF, Hollister EB, Bryan RM. " " Hypertension. 2016 ;
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Durgan DJ, Crossland RF, Bryan RM.. " " J Cereb Blood Flow Metab.. 2016 ;
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Lloyd EE, Durgan DJ, Martini SR, Bryan RM.. " " Hypertension. 2015 ;
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Durgan DJ, Crossland RF, Lloyd EE, Phillips SC, Bryan RM.. " " J Cereb Blood Flow Metab. 2015 ;
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Crossland RF, Durgan DJ, Lloyd EE, Phillips SC, Reddy AK, Marrelli SP, Bryan RM.. " " Am J Physiol Regul Integr Comp Physiol.. 2013 ;
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Durgan DJ, Bryan RM. " " J Am Heart Assoc.. 2012 ;
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Durgan DJ, Pat BM, Laczy B, Bradley JA, Tsai JY, Grenett MH, Ratcliffe WF, Brewer RA, Nagendran J, Villegas-Montoya C, Zou C, Zou L, Johnson RL, Dyck JR, Bray MS, Gamble KL, Chatham JC, Young ME.. " " J Biol Chem.. 2011 ;
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Durgan DJ, Tsai JY, Grenett MH, Pat BM, Ratcliffe WF, Villegas-Montoya C, Garvey ME, Nagendran J, Dyck JR, Bray MS, Gamble KL, Gimble JM, Young ME. " " Chronobiol Int.. 2011 ;
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Durgan DJ, Young ME. " " Circ Res.. 2010 ;
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Durgan DJ, Pulinilkunnil T, Villegas-Montoya C, Garvey ME, Frangogiannis NG, Michael LH, Chow CW, Dyck JR, Young ME. " " Circ Res.. 2010 ;
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Tsai JY, Kienesberger PC, Pulinilkunnil T, Sailors MH, Durgan DJ, Villegas-Montoya C, Jahoor A, Gonzalez R, Garvey ME, Boland B, Blasier Z, McElfresh TA, Nannegari V, Chow CW, Heird WC, Chandler MP, Dyck JR, Bray MS, Young ME.. " " J Biol Chem.. 2010 ;
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Lockridge JB, Sailors ML, Durgan DJ, Egbejimi O, Jeong WJ, Bray MS, Stanley WC, Young ME.. " " J Lipid Res.. 2008 ;
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Durgan DJ, Young ME.. " " Cardiovasc Drugs Ther.. 2008 ;
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Bray MS, Shaw CA, Moore MW, Garcia RA, Zanquetta MM, Durgan DJ, Jeong WJ, Tsai JY, Bugger H, Zhang D, Rohrwasser A, Rennison JH, Dyck JR, Litwin SE, Hardin PE, Chow CW, Chandler MP, Abel ED, Young ME. " " Am J Physiol Heart Circ Physiol.. 2008 ;
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Kung TA, Egbejimi O, Cui J, Ha NP, Durgan DJ, Essop MF, Bray MS, Shaw CA, Hardin PE, Stanley WC, Young ME.. " " J Mol Cell Cardiol.. 2007 ;
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Durgan DJ, Moore MW, Ha NP, Egbejimi O, Fields A, Mbawuike U, Egbejimi A, Shaw CA, Bray MS, Nannegari V, Hickson-Bick DL, Heird WC, Dyck JR, Chandler MP, Young ME.. " " Am J Physiol Heart Circ Physiol.. 2007 ;
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Durgan DJ, Trexler NA, Egbejimi O, McElfresh TA, Suk HY, Petterson LE, Shaw CA, Hardin PE, Bray MS, Chandler MP, Chow CW, Young ME. " " J Biol Chem.. 2006 ;
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Durgan DJ, Smith JK, Hotze MA, Egbejimi O, Cuthbert KD, Zaha VG, Dyck JR, Abel ED, Young ME.. " " Am J Physiol Heart Circ Physiol.. 2006 ;
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Durgan DJ, Hotze MA, Tomlin TM, Egbejimi O, Graveleau C, Abel ED, Shaw CA, Bray MS, Hardin PE, Young ME.. " " Am J Physiol Heart Circ Physiol.. 2005 ;
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Memberships

American Heart Association

American Physiological Society

Texas Medical Center Digestive Disease Center

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