George E Taffet

George E Taffet, M.D.

Robert J. Luchi, M.D. Chair

(713) 798-3967

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Email

gtaffet@bcm.edu

Positions

Robert J. Luchi, M.D. Chair: Geriatric Medicine
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Professor: Medicine-Geriatrics
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Addresses

Baylor Clinic Bldg (Office): BCM Academic Office
6620 Main St.
Houston, TX, 77030
United States
Phone: (713) 798-2293
gtaffet@bcm.edu
Geriatrics website

Education

Residency at ��vlog�� of Medicine: 06/1985 - Houston, TX, United States; Internal Medicine

Internship at ��vlog�� of Medicine: 06/1983 - Houston, TX, United States; Internal Medicine

MD from Brown University Program in Medicine: 01/1982 - Providence, RI, United States

Clinical Fellowship at ��vlog�� of Medicine: 06/1987 - Houston, United States; Geriatric

Post-Doctoral Fellowship at ��vlog�� of Medicine: 06/1998 - Houston, United States; Research Fellowship-Cardiovascular Sciences

Certifications

Internal Medicine: American Board of Internal Medicine

Geriatrics: American Board of Internal Medicine

Honors & Awards

Barbara and Corbin J. Robertson, Jr. Presidential Award for Excellence In Education: ��vlog�� of Medicine (05/2011)

Professional Interests

Heart failure: Calcium and aging
Vascular aging
Physiology and Biochemistry: using mouse models of human aging and disease

Professional Statement

I have been at BCM since 1982 for my internal medicine training, clinical Geriatrics fellowship, fellowship in cardiovascular research and on the faculty. At ��vlog�� of Medicine I lead and give all the aging lectures in ARTS (age-related themes) as the culmination of the didactic experience in the medical student’s second year, and I provide clinical opportunities to learn from and about old people all across the care spectrum. This includes house calls, independent living facilities, nursing homes, the hospital and the hospice. I teach Baylor and Methodist medicine residents as an Attending Physician, in conferences, and at the VA and Methodist morning report. I am also a faculty member in the Huffington Center of Aging Biology of Aging Graduate Program, the Physiology Graduate Program, and the Translational Biology and Molecular Medicine Graduate Program.
My research interests have been in the area of cardiovascular aging. My early interests centered on aging and endurance exercise training for rats and how exercise improved the heart's ability to fill, its diastolic function. I have remained interested in diastole as heart failure due to diastolic dysfunction is the most common type of heart failure for older people, impacts quality of life and survival, and there are no drugs to treat it. Our approach is to address the underlying aging change that is additive to any disease mediated changes. I am also interested in large artery stiffening with age. Both the artery and cardiac investigations are done in young, old and transgenic mice. However, the goal is clearly to improve the condition of the older people. Additionally, as our group has developed many of the techniques to assess cardiac function in mice, we are a resource to a number of investigators across the Texas Medical Center.

Websites

Geriatrics Care Center

Selected Publications

Swan JT, Wagle KC, Thompson-Moore N, Taffet GE. " " J Hosp Med. 2013 Jun ; 8 (6) : 304-8.
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Cieslik KA, Trial J, Carlson S, Taffet GE, Entman ML. " " FASEB J.. 2013 Apr ; 27 (4) : 1761-71.
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Duerrschmid C, Crawford JR, Reineke E, Taffet GE, Trial J, Entman ML, Haudek SB. " " J. Mol. Cell. Cardiol.. 2013 Apr ; 57 : 59-67.
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Mills WL, Roush RE, Moye J, Kunik ME, Wilson NL, Taffet GE, Naik AD. " " Gerontol Geriatr Educ. 2012 Oct ; 33 (4) : 351-63.
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Kerfoot BP, Baker H, Pangaro L, Agarwal K, Taffet G, Mechaber AJ, Armstrong EG. " " Acad Med. 2012 Oct ; 87 (10) : 1443-9.
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Reineke EL, York B, Stashi E, Chen X, Tsimelzon A, Xu J, Newgard CB, Taffet GE, Taegtmeyer H, Entman ML, O'Malley BW. " " PLoS ONE. 2012 ; 7 (12) : e53395.
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Gurha P, Abreu-Goodger C, Wang T, Ramirez MO, Drumond AL, van Dongen S, Chen Y, Bartonicek N, Enright AJ, Lee B, Kelm RJ, Reddy AK, Taffet GE, Bradley A, Wehrens XH, Entman ML, Rodriguez A. " " Circulation. 2012 Jun 5; 125 (22) : 2751-61.
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Lloyd EE, Crossland RF, Phillips SC, Marrelli SP, Reddy AK, Taffet GE, Hartley CJ, Bryan RM. " " Hypertension. 2011 Oct ; 58 (4) : 672-8.
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Sekhar RV, Patel SG, Guthikonda AP, Reid M, Balasubramanyam A, Taffet GE, Jahoor F. " " Am. J. Clin. Nutr.. 2011 Sep ; 94 (3) : 847-53.
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Xu J, Lin SC, Chen J, Miao Y, Taffet GE, Entman ML, Wang Y. " " Am. J. Physiol. Heart Circ. Physiol.. 2011 Aug ; 301 (2) : H538-47.
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Hartley CJ, Reddy AK, Madala S, Entman ML, Michael LH, Taffet GE. " " Am. J. Physiol. Heart Circ. Physiol.. 2011 Aug ; 301 (2) : H269-78.
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Cheema FN, Abraham NS, Berger DH, Albo D, Taffet GE, Naik AD. " " Ann. Surg.. 2011 May ; 253 (5) : 867-74.
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Cieslik KA, Taffet GE, Carlson S, Hermosillo J, Trial J, Entman ML. " " J. Mol. Cell. Cardiol.. 2011 Jan ; 50 (1) : 248-56.
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Smiechowska J, Utech A, Taffet G, Hayes T, Marcelli M, Garcia JM. " " J. Investig. Med.. 2010 Mar ; 58 (3) : 554-9.
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Alexander NB, Taffet GE, Horne FM, Eldadah BA, Ferrucci L, Nayfield S, Studenski S. " " J Am Geriatr Soc. 2010 May ; 58 (5) : 967-75.
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Chintalgattu V, Ai D, Langley RR, Zhang J, Bankson JA, Shih TL, Reddy AK, Coombes KR, Daher IN, Pati S, Patel SS, Pocius JS, Taffet GE, Buja LM, Entman ML, Khakoo AY. " " J. Clin. Invest.. 2010 Feb 1; 120 (2) : 472-84.
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Namiranian K, Lloyd EE, Crossland RF, Marrelli SP, Taffet GE, Reddy AK, Hartley CJ, Bryan RM. " " Am. J. Physiol. Regul. Integr. Comp. Physiol.. 2010 Aug ; 299 (2) : R461-9.
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Hartley CJ, Reddy AK, Michael LH, Entman ML, Chintalagattu V, Khakoo AY, Taffet GE. " " Conf Proc IEEE Eng Med Biol Soc. 2010 ; 1 : 3780-3.
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Wagle KC, Natali B, Taffet GE. " " J Am Geriatr Soc. 2011 Oct ; 59 (10) : 1988-9.
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Bujak M, Kweon HJ, Chatila K, Li N, Taffet G, Frangogiannis NG. " " J. Am. Coll. Cardiol.. 2008 Apr 8; 51 (14) : 1384-92.
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Weisleder N, Taffet GE, Capetanaki Y. " " Proc. Natl. Acad. Sci. U.S.A.. 2004 Jan 20; 101 (3) : 769-74.
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Hyman DJ, Taffet GE. " " Curr. Hypertens. Rep.. 2009 Oct ; 11 (5) : 337-42.
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Reddy AK, Amador-Noguez D, Darlington GJ, Scholz BA, Michael LH, Hartley CJ, Entman ML, Taffet GE. " " J. Gerontol. A Biol. Sci. Med. Sci.. 2007 Dec ; 62 (12) : 1319-25.
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Taffet GE, Tate CA. " " Am. J. Physiol.. 1993 May ; 264 (5) : H1609-14.
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Memberships

American Association for the Advancement of Science

American Geriatrics Society: Research Committee

Gerontological Society of America: Past Chair, Research Committee

American Federation for Aging Research

Association of Directors of Geriatric Academic Programs

American Heart Association: Basic Science Council

Texas Geriatrics Society: Former Board Member

American Association of Home Care Physicians

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