Positions
- Associate Professor
-
Department of Ophthalmology
ÌÇÐÄvlogÃÛÌÒ of Medicine
Houston, Texas, United States
Addresses
- Neurosensory Center (Office)
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ÌÇÐÄvlogÃÛÌÒ of Medicine
Houston, TX, 77030
United States
Phone: (713) 798-5527
Education
- MD from Medical school, Xi'an Jiaotong University
- Xi'an, P. R. China
- PhD from Medical school, Xi'an Jiaotong University
- Xi'an, P. R. China
- Postdoctoral Fellowship at ÌÇÐÄvlogÃÛÌÒ of Medicine
- 01/2000 - Houston, Texas, United States
- Neurology
- Postdoctoral Fellowship at ÌÇÐÄvlogÃÛÌÒ of Medicine
- Houston, Texas, United States
- Ophthalmology
Professional Interests
- Complete identification of all retinal neurons with light-evoked activities and morphological features
- Retinal ion channels, synapses and neuronal circuitry
- Mechanosensitive ion channels in retinal function and diseases
Professional Statement
My work focuses on retinal visual signaling in physiological and pathological conditions. I characterize retinal photoreceptors, bipolar cells, amacrine cells, and ganglion cells with light-evoked activities and single-cell immunofluorescence. Based on such neuronal identities, I further study the signaling between photoreceptors and bipolar cells and synapses among bipolar cells, amacrine cells, and ganglion cells, primarily by using one- to eight-cell patch-clamp technologies, in conjunction with genetic engineering, electron microscopy, confocal microscopy, and immunocytochemistry. Built on these physiological data, my study further explores the role of mechanical-sensitive ion channels in normal retinal visual functions and the pathogenesis of glaucoma, traumatic retinal injury, and other pressure-related retinal disorders.
Websites
Selected Publications
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Frankfort BJ, Khan AK, Tse DY, Chung I, Pang JJ, Yang Z, Gross RL, Wu SM. " " Invest. Ophthalmol. Vis. Sci.. 2013 ; 54 (1) : 762-70.
Pubmed PMID: . -
Pang JJ, Gao F, Lem J, Bramblett DE, Paul DL, Wu SM. " " Proc. Natl. Acad. Sci. U.S.A.. 2010 Jan 5; 107 (1) : 395-400.
Pubmed PMID: . -
Pang JJ, Gao F, Wu SM. " " J. Neurosci.. 2003 Jul 9; 23 (14) : 6063-73.
Pubmed PMID: . -
Pang JJ, Gao F, Wu SM. " " J. Neurosci.. 2002 Jun 1; 22 (11) : 4693-701.
Pubmed PMID: .
Memberships
- Association for Research in Vision and Ophthalmology
- Member
- Society for Neuroscience
- Member
- Royal Society of Medicine (London)
- Member
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