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Matthew Torre

Torre

Matthew Torre

Assistant Professor

Email

matthew.torre@bcm.edu

Positions

Assistant Professor
Pathology and Immunology
ÌÇÐÄvlogÃÛÌÒ of Medicine
Houston, Texas, United States
Investigator
Jan and Dan Duncan Neurological Research Institute
Texas Children's Hospital
Faculty Member
Center for Alzheimer's and Neurodegenerative Diseases (CAND)
ÌÇÐÄvlogÃÛÌÒ of Medicine

Addresses

Duncan Neurological Research Institute (Lab)
1250 Moursund Street
DNRI-N.0650.28
Houston, TX, 77030
United States

Education

MD from Harvard Medical School
Boston, Massachusetts, United States
BA from University of Pennsylvania
Philadelphia, Pennsylvania, United States
Residency at Brigham and Women's Hospital
Boston, Massachusetts, United States
Anatomic Pathology
Clinical Fellowship at Brigham and Women's Hospital, Boston Children's Hospital
Boston, Massachusetts, United States
Neuropathology
Postdoctoral Fellowship at Brigham and Women's Hospital
Boston, Massachusetts, United States

Professional Interests

  • Chemotherapy-related cognitive impairment
  • Neurodegeneration
  • Iatrogenic neuropathology

Professional Statement

Chemotherapy-related cognitive impairment (CRCI) is an increasingly recognized adverse effect of treatment and is observed in up to 75% of patients. Despite the high frequency of CRCI and its associated patient morbidity, the pathophysiology of CRCI is incompletely understood. However, CRCI and neurodegenerative disorders such as Alzheimer's disease plausibly share biological mechanisms, and prior chemotherapy exposure may mediate future risk of dementia. The goal of the Torre laboratory is to dissect mechanisms contributing to CRCI and neurodegeneration and develop therapeutic strategies to preserve cognition in patients at risk of cognitive decline. The laboratory performs studies in complementary organismal model systems, including Drosophila and murine models, and human brain tissue.

Websites

Comprehensive list of publications

Selected Publications

  • Torre M, Bukhari H, Nithianandam V, Zanella CA, Mata DA, Feany MB. " " Sci Rep. 2023 Nov 7; 13 (1) : 19290.
    Pubmed PMID: .
  • Torre M, Dey A, Woods JK, Feany MB. " " J Neuropathol Exp Neurol. 2021 Aug 11; 80 (7) : 705-712.
    Pubmed PMID: .
  • Torre M, Feany MB. " " Surg Pathol Clin. 2020 Jun ; 13 (2) : 331-342.
    Pubmed PMID: .

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