ÌÇÐÄvlogÃÛÌÒ

Email

Positions

Professor and Core Director

ÌÇÐÄvlogÃÛÌÒ of Medicine
Houston, Texas, United States

Addresses

BCM-Cullen Building (Office)

Room: BCMC-119A
Houston, TX, 77030
United States
Phone: (713) 408-0179
mancini@bcm.edu
/people/view/b207808c-ffed-11e2-be68-080027880ca6/53f64f3f-a3d4-4102-8eaa-1e1e0a1612dc

BCM-Cullen Building (Lab)

Room: BCMC-119A
Houston, TX, 77030
United States
Phone: (713) 408-0179
mancini@bcm.edu
/people/view/b207808c-ffed-11e2-be68-080027880ca6/53f64f3f-a3d4-4102-8eaa-1e1e0a1612dc

Education

PhD from University Of Texas Health Science Center

01/1991 - San Antonio, TX, United States

Cellular and Structural Biology

Honors & Awards

Professor

My group's interests revolve around single cell analysis of gene expression, primarily through native or engineered estrogen receptor model systems. Model systems are designed for use with quantitative, high content analysis using a wide range of imaging platforms, ranging from high throughput microscopy to multiple super resolution platforms (SIM, STED, STORM) followed by image analysis, data mining and classifications approaches, including deep learning and neural networks. Current funding centers around use of the above approaches to detect/quantify/classify endocrine disrupting chemicals (EDCs) in flood waters associated with Galveston Bay and the Houston Ship Channel.

ÌÇÐÄvlogÃÛÌÒ of Medicine (05/1995)

Professional Interests

• Single cell analysis of gene regulation

Websites

Selected Publications

• Nazareth LV, Stenoien DL, Bingman WE, James AJ, Wu C, Zhang Y, Edwards DP, Mancini M, Marcelli M, Lamb DJ, Weigel NL. " " Mol. Endocrinol.. 1999 Dec ; 13 (12) : 2065-75.
  Pubmed PMID: .
• Slattery SD, Newberg JY, Szafran AT, Hall RM, Brinkley BR, Mancini MA. " " Assay Drug Dev Technol. 2012 Apr ; 10 (2) : 161-78.
  Pubmed PMID: .
• Berno V, Amazit L, Hinojos C, Zhong J, Mancini MG, Sharp ZD, Mancini MA. " " PLoS ONE. 2008 ; 3 (5) : e2286.
  Pubmed PMID: .
• Mancini MA, Chatterjee B, Roy AK. " " J. Histochem. Cytochem.. 1991 Apr ; 39 (4) : 401-5.
  Pubmed PMID: .
• Mancini MA, Majumdar D, Chatterjee B, Roy AK. " " J. Histochem. Cytochem.. 1989 Feb ; 37 (2) : 149-57.
  Pubmed PMID: .
• Hartig SM, He B, Long W, Buehrer BM, Mancini MA. " " J. Cell Biol.. 2011 Jan 10; 192 (1) : 55-67.
  Pubmed PMID: .
• Van Hooser A, Goodrich DW, Allis CD, Brinkley BR, Mancini MA. " " J. Cell. Sci.. 1998 Dec ; 111 : 3497-506.
  Pubmed PMID: .
• Berno V, Hinojos CA, Amazit L, Szafran AT, Mancini MA. " " Meth. Enzymol.. 2006 ; 414 : 188-210.
  Pubmed PMID: .
• Ashcroft FJ, Newberg JY, Jones ED, Mikic I, Mancini MA. " " Gene. 2011 May 15; 477 (41276) : 42-52.
  Pubmed PMID: .
• Giordano C, Cui Y, Barone I, Ando S, Mancini MA, Berno V, Fuqua SA. " " Breast Cancer Res. Treat.. 2010 Jan ; 119 (1) : 71-85.
  Pubmed PMID: .
• Van Hooser AA, Mancini MA, Allis CD, Sullivan KF, Brinkley BR. " " FASEB J.. 1999 Dec ; 13 : S216-20.
  Pubmed PMID: .
• Zwart W, de Leeuw R, Rondaij M, Neefjes J, Mancini MA, Michalides R. " " J. Cell. Sci.. 2010 Apr 15; 123 : 1253-61.
  Pubmed PMID: .
• Contreras A, Hale TK, Stenoien DL, Rosen JM, Mancini MA, Herrera RE. " " Mol. Cell. Biol.. 2003 Dec ; 23 (23) : 8626-36.
  Pubmed PMID: .
• Lee WH, Xu Y, Hong F, Durfee T, Mancini MA, Ueng YC, Chen PL, Riley D. " " Cold Spring Harb. Symp. Quant. Biol.. 1994 ; 59 : 97-107.
  Pubmed PMID: .
• Herrmann CH, Mancini MA. " " J. Cell. Sci.. 2001 Apr ; 114 : 1491-503.
  Pubmed PMID: .
• Zhu X, Chang KH, He D, Mancini MA, Brinkley WR, Lee WH. " " J. Biol. Chem.. 1995 Aug 18; 270 (33) : 19545-50.
  Pubmed PMID: .
• Durfee T, Mancini MA, Jones D, Elledge SJ, Lee WH. " " J. Cell Biol.. 1994 Nov ; 127 (3) : 609-22.
  Pubmed PMID: .
• Mediwala SN, Sun H, Szafran AT, Hartig SM, Sonpavde G, Hayes TG, Thiagarajan P, Mancini MA, Marcelli M. " " Prostate. 2013 Feb 15; 73 (3) : 267-77.
  Pubmed PMID: .
• Magnuson VL, Young M, Schattenberg DG, Mancini MA, Chen DL, Steffensen B, Klebe RJ. " " J. Biol. Chem.. 1991 Aug 5; 266 (22) : 14654-62.
  Pubmed PMID: .
• Chatterjee B, Song CS, Jung MH, Chen S, Walter CA, Herbert DC, Weaker FJ, Mancini MA, Roy AK. " " Proc. Natl. Acad. Sci. U.S.A.. 1996 Jan 23; 93 (2) : 728-33.
  Pubmed PMID: .
• Stenoien DL, Mancini MG, Patel K, Allegretto EA, Smith CL, Mancini MA. " " Mol. Endocrinol.. 2000 Apr ; 14 (4) : 518-34.
  Pubmed PMID: .
• Mancini MG, Liu B, Sharp ZD, Mancini MA. " " J. Cell. Biochem.. 1999 Mar 1; 72 (3) : 322-38.
  Pubmed PMID: .
• Stenoien DL, Simeoni S, Sharp ZD, Mancini MA. " " J. Cell. Biochem. Suppl.. 2000 ; 99-106.
  Pubmed PMID: .
• Long W, Yi P, Amazit L, LaMarca HL, Ashcroft F, Kumar R, Mancini MA, Tsai SY, Tsai MJ, O'Malley BW. " " Mol. Cell. 2010 Feb 12; 37 (3) : 321-32.
  Pubmed PMID: .
• Mancini MA, Song CS, Rao TR, Chatterjee B, Roy AK. " " Endocrinology. 1992 Sep ; 131 (3) : 1541-6.
  Pubmed PMID: .
• Murty CV, Sarkar FH, Mancini MA, Roy AK. " " Endocrinology. 1987 Sep ; 121 (3) : 1000-5.
  Pubmed PMID: .
• Roy AK, Sarkar FH, Nag AC, Mancini MA. " " Prog. Clin. Biol. Res.. 1986 ; 226 : 401-15.
  Pubmed PMID: .
• Amazit L, Pasini L, Szafran AT, Berno V, Wu RC, Mielke M, Jones ED, Mancini MG, Hinojos CA, O'Malley BW, Mancini MA. " " Mol. Cell. Biol.. 2007 Oct ; 27 (19) : 6913-32.
  Pubmed PMID: .
• Marcelli M, Stenoien DL, Szafran AT, Simeoni S, Agoulnik IU, Weigel NL, Moran T, Mikic I, Price JH, Mancini MA. " " J. Cell. Biochem.. 2006 Jul 1; 98 (4) : 770-88.
  Pubmed PMID: .
• Stenoien DL, Cummings CJ, Adams HP, Mancini MG, Patel K, DeMartino GN, Marcelli M, Weigel NL, Mancini MA. " " Hum. Mol. Genet.. 1999 May ; 8 (5) : 731-41.
  Pubmed PMID: .
• Prigozhina NL, Zhong L, Hunter EA, Mikic I, Callaway S, Roop DR, Mancini MA, Zacharias DA, Price JH, McDonough PM. " " Assay Drug Dev Technol. 2007 Feb ; 5 (1) : 29-48.
  Pubmed PMID: .
• Hinojos CA, Sharp ZD, Mancini MA. " " Trends Endocrinol. Metab.. ; 16 (1) : 41616.
  Pubmed PMID: .
• Hendzel MJ, Wei Y, Mancini MA, Van Hooser A, Ranalli T, Brinkley BR, Bazett-Jones DP, Allis CD. " " Chromosoma. 1997 Nov ; 106 (6) : 348-60.
  Pubmed PMID: .
• Stenoien DL, Nye AC, Mancini MG, Patel K, Dutertre M, O'Malley BW, Smith CL, Belmont AS, Mancini MA. " " Mol. Cell. Biol.. 2001 Jul ; 21 (13) : 4404-12.
  Pubmed PMID: .
• García-Becerra R, Berno V, Ordaz-Rosado D, Sharp ZD, Cooney AJ, Mancini MA, Larrea F. " " Gene. 2010 Jun 15; 458 (41276) : 37-44.
  Pubmed PMID: .
• Stenoien DL, Mielke M, Mancini MA. " " Nat. Cell Biol.. 2002 Oct ; 4 (10) : 806-10.
  Pubmed PMID: .
• Sharp ZD, Stenoien DL, Mancini MG, Ouspenski II, Mancini MA. " " J. Cell. Biochem.. 2004 Jul 1; 92 (4) : 664-78.
  Pubmed PMID: .
• Stenoien D, Sharp ZD, Smith CL, Mancini MA. " " J. Cell. Biochem.. 1998 Aug 1; 70 (2) : 213-21.
  Pubmed PMID: .
• Stenoien DL, Patel K, Mancini MG, Dutertre M, Smith CL, O'Malley BW, Mancini MA. " " Nat. Cell Biol.. 2001 Jan ; 3 (1) : 15-23.
  Pubmed PMID: .
• Hartig SM, He B, Newberg JY, Ochsner SA, Loose DS, Lanz RB, McKenna NJ, Buehrer BM, McGuire SE, Marcelli M, Mancini MA. " " Chem. Biol.. 2012 Sep 21; 19 (9) : 1126-41.
  Pubmed PMID: .
• Sharp ZD, Mancini MG, Hinojos CA, Dai F, Berno V, Szafran AT, Smith KP, Lele TP, Lele TT, Ingber DE, Mancini MA. " " J. Cell. Sci.. 2006 Oct 1; 119 : 4101-16.
  Pubmed PMID: .
• Dong S, Qiu J, Stenoien DL, Brinkley WR, Mancini MA, Tweardy DJ. " " Oncogene. 2003 Feb 13; 22 (6) : 858-68.
  Pubmed PMID: .
• Mancini MA, He D, Ouspenski II, Brinkley BR. " " J. Cell. Biochem.. 1996 Aug ; 62 (2) : 158-64.
  Pubmed PMID: .
• Stenoien DL, Sen S, Mancini MA, Brinkley BR. " " Cell Motil. Cytoskeleton. 2003 Jun ; 55 (2) : 134-46.
  Pubmed PMID: .
• Narayanan R, Yepuru M, Szafran AT, Szwarc M, Bohl CE, Young NL, Miller DD, Mancini MA, Dalton JT. " " Cancer Res.. 2010 Jan 15; 70 (2) : 842-51.
  Pubmed PMID: .
• McDonough PM, Maciejewski-Lenoir D, Hartig SM, Hanna RA, Whittaker R, Heisel A, Nicoll JB, Buehrer BM, Christensen K, Mancini MG, Mancini MA, Edwards DP, Price JH. " " PLoS ONE. 2013 ; 8 (2) : e55511.
  Pubmed PMID: .
• Kazansky AV, Kabotyanski EB, Wyszomierski SL, Mancini MA, Rosen JM. " " J. Biol. Chem.. 1999 Aug 6; 274 (32) : 22484-92.
  Pubmed PMID: .
• Ho TH, Savkur RS, Poulos MG, Mancini MA, Swanson MS, Cooper TA. " " J. Cell. Sci.. 2005 Jul 1; 118 : 2923-33.
  Pubmed PMID: .
• Bolt MJ, Stossi F, Newberg JY, Orjalo A, Johansson HE, Mancini MA. " " Nucleic Acids Res.. 2013 Apr 1; 41 (7) : 4036-48.
  Pubmed PMID: .
• Zhu X, Mancini MA, Chang KH, Liu CY, Chen CF, Shan B, Jones D, Yang-Feng TL, Lee WH. " " Mol. Cell. Biol.. 1995 Sep ; 15 (9) : 5017-29.
  Pubmed PMID: .
• Cummings CJ, Mancini MA, Antalffy B, DeFranco DB, Orr HT, Zoghbi HY. " " Nat. Genet.. 1998 Jun ; 19 (2) : 148-54.
  Pubmed PMID: .
• Murty CV, Mancini MA, Chatterjee B, Roy AK. " " Biochim. Biophys. Acta. 1988 Jan 25; 949 (1) : 27-34.
  Pubmed PMID: .
• Unni E, Sun S, Nan B, McPhaul MJ, Cheskis B, Mancini MA, Marcelli M. " " Cancer Res.. 2004 Oct 1; 64 (19) : 7156-68.
  Pubmed PMID: .
• Sarkar FH, Mancini MA, Nag AC, Roy AK. " " J. Endocrinol.. 1986 Nov ; 111 (2) : 205-8.
  Pubmed PMID: .
• Uray IP, Rodenberg JM, Bissonnette RP, Brown PH, Mancini MA. " " Mol. Pharmacol.. 2012 Feb ; 81 (2) : 228-38.
  Pubmed PMID: .
• Chen W, Chang B, Saha P, Hartig SM, Li L, Reddy VT, Yang Y, Yechoor V, Mancini MA, Chan L. " " Mol. Cell. Biol.. 2012 Mar ; 32 (6) : 1099-111.
  Pubmed PMID: .
• Hartig SM, Newberg JY, Bolt MJ, Szafran AT, Marcelli M, Mancini MA. " " Methods Mol. Biol.. 2011 ; 776 : 313-31.
  Pubmed PMID: .
• Slattery SD, Mancini MA, Brinkley BR, Hall RM. " " Cell Cycle. 2009 Sep 15; 8 (18) : 2984-94.
  Pubmed PMID: .
• Das A, Frank RN, Weber ML, Kennedy A, Reidy CA, Mancini MA. " " Exp. Eye Res.. 1988 Mar ; 46 (3) : 349-62.
  Pubmed PMID: .
• Szafran AT, Hartig S, Sun H, Uray IP, Szwarc M, Shen Y, Mediwala SN, Bell J, McPhaul MJ, Mancini MA, Marcelli M. " " PLoS ONE. 2009 ; 4 (12) : e8179.
  Pubmed PMID: .
• Szafran AT, Sun H, Hartig S, Shen Y, Mediwala SN, Bell J, McPhaul MJ, Mancini MA, Marcelli M. " " Adv. Exp. Med. Biol.. 2011 ; 707 : 63-5.
  Pubmed PMID: .
• Song CS, Rao TR, Demyan WF, Mancini MA, Chatterjee B, Roy AK. " " Endocrinology. 1991 Jan ; 128 (1) : 349-56.
  Pubmed PMID: .
• Szafran AT, Szwarc M, Marcelli M, Mancini MA. " " PLoS ONE. 2008 ; 3 (11) : e3605.
  Pubmed PMID: .
• Nye AC, Rajendran RR, Stenoien DL, Mancini MA, Katzenellenbogen BS, Belmont AS. " " Mol. Cell. Biol.. 2002 May ; 22 (10) : 3437-49.
  Pubmed PMID: .
• Mancini MA, Shan B, Nickerson JA, Penman S, Lee WH. " " Proc. Natl. Acad. Sci. U.S.A.. 1994 Jan 4; 91 (1) : 418-22.
  Pubmed PMID: .
• Boonyaratanakornkit V, McGowan E, Sherman L, Mancini MA, Cheskis BJ, Edwards DP. " " Mol. Endocrinol.. 2007 Feb ; 21 (2) : 359-75.
  Pubmed PMID: .
• Chatterjee B, Mancini MA, Roy AK. " " Biochim. Biophys. Acta. 1990 May 16; 1034 (2) : 162-9.
  Pubmed PMID: .

Funding

Center for Advanced Microscopy and Image Informatics

Grant funding from CPRIT

Skills

Michael A. Mancini