Positions
- Professor
-
Pediatrics-Hem-Onc Cell & Gene
ÌÇÐÄvlogÃÛÌÒ of Medicine
Houston, TX, US
- Member
-
Dan L Duncan Comprehensive Cancer Center
ÌÇÐÄvlogÃÛÌÒ of Medicine
Houston, Texas, United States
Addresses
- TX Childs Feigin Ctr (Office)
-
Room: TXFC-176012
Houston, TX, 77030
United States
- Texas Children's Hospital, Clinical Care Center (Clinic)
-
6701 Fannin St
14th floor
Houston, TX, 77030
United States
Phone: (832) 822-4242
Professional Interests
- Bone Marrow Transplantation
- Cell and Gene Therapy
Professional Statement
Dr. Ahmed is a physician scientist engaged in translational research focusing on adoptive immunotherapy with gene-modified effector cells, to improve therapy for brain tumors. Dr Ahmed's initial studies demonstrated that antigen-specific cytotoxic T cells could eradicate established brain tumors in medulloblastoma and Glioblastoma models. Subsequent studies have demonstrated that the tumor-specific T cells, unlike conventional therapies, can effectively target the stem cell compartment in the tumor eradicating experimental tumors in animal models. Aligning with his primary interest is studying the role of T cells in creating a tumor niche and studying T cell migration to distant tumor sites in the brain. Dr. Ahmed therefore has experience in developing and translating cell and gene therapy studies to the clinic. Currently, Dr. Ahmed is the principal investigator on 3 clinical trials targeting Glioblastoma and Osteosarcoma by administering tumor-specific T cells to. All studies are FDA, IRB, RAC and IBC approved.
Websites
Selected Publications
-
Fu X, Tao L, Rivera A, Williamson S, Song XT, Ahmed N, Zhang X. " " PLoS ONE. 2010 ; 5 (7) : e11867.
Pubmed PMID: . -
Ahmed N, Chizhevsky V. " " J. Pediatr. Hematol. Oncol.. 2007 Oct ; 29 (10) : 720-4.
Pubmed PMID: . -
Salsman VS, Chow KK, Shaffer DR, Kadikoy H, Li XN, Gerken C, Perlaky L, Metelitsa LS, Gao X, Bhattacharjee M, Hirschi K, Heslop HE, Gottschalk S, Ahmed N. " " PLoS ONE. 2011 ; 6 (5) : e20267.
Pubmed PMID: . -
Ghazi A, Ashoori A, Hanley PJ, Brawley VS, Shaffer DR, Kew Y, Powell SZ, Grossman R, Grada Z, Scheurer ME, Hegde M, Leen AM, Bollard CM, Rooney CM, Heslop HE, Gottschalk S, Ahmed N. " " J. Immunother.. 2012 Feb ; 35 (2) : 159-68.
Pubmed PMID: .
to edit your profile