Rajagopal V. Sekhar

Rajagopal V. Sekhar, M.D.

Professor of Medicine

Email

rsekhar@bcm.edu

Positions

Professor of Medicine: Endocrinology, Diabetes and Metabolism
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Houston, TX, USA

Lead: Translational Metabolism Unit
Endocrinology, Diabetes and Metabolism
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Houston, TX, USA

Faculty and Clinic Head: Endocrine and Metabolic Disorders Clinic
Quentin Meese Health Center
Houston, TX, USA

Faculty: Endocrinology and Metabolism
Ben Taub General Hospital
Harris Health System
Houston, TX, USA

Secondary Faculty: Huffington Center on Aging
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Houston, TX, USA

Member: Texas Development Center for AIDS Research (Texas D-CFAR)
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Houston, TX, USA

Member: Center of Alzheimer and Neurodegenerative Diseases (CAND)
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Houston, TX, USA

Core Faculty: Endocrinology, Diabetes and Metabolism
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Houston, TX, USA

Addresses

��vlog�� of Medicine (Office): MS BCM-185, Section of Endocrinology, Diabetes and Metabolism
Translational Metabolism Unit
Houston, TX, 77030-3411
United States
rsekhar@bcm.edu

Education

MBBS from St. John's Medical College, 1986-1991 (Doctor of Medicine degree): Bangalore, India; Doctor of Medicine

Internship at St. John's Medical College Hospital (1991-1992): Bangalore, India

Postdoctoral Training at Nutrition Resarch Center, St. John's Medical College (1992-1995): Bangalore, India

Residency at Internal Medicine (1995-1998): United Kingdom

Clinical Fellowship at ��vlog�� of Medicine (1998-2000): Houston, TX, USA; Endocrinology and Metabolism

Fellowship at ��vlog�� of Medicine (2000-2001): Houston, TX, USA; Research Fellowship in Nutritional Metabolism

Residency at University of Oklahoma College of Medicine (2001-2003): Tulsa, OK, USA; Internal Medicine

Certifications

American Board of Medical Specialties

American Board of Internal Medicine

Honors & Awards

1992: The Dr. and Mrs. Menino D’Souza Prize: Best graduating medical student; St. John’s Medical College, Bangalore India.

1991: The Dr. H. J. Mehta Research Prize: Best research work by a medical student; St. John’s Medical College, Bangalore India.

2001: Outstanding Fellow in Endocrinology Special Recognition Award: Conferred by the Endocrine Fellows Forum of Excellence for ‘outstanding academic and professional achievements and commitment to diabetes research and management’, at the Annual Scientific Meeting of the American Diabetes Association, Philadelphia, PA.; Endocrine Fellows Forum of Excellence

2001: The Pfizer Scholar in Endocrinology National Award: Presented ‘In recognition of outstanding achievement in the advancement of Endocrine Science’.

2001: First Place and Third Place Awards: Annual Scientific Session of the American College of Medicine and American Society of Internal Medicine (ACP-ASIM, Oklahoma Chapter), Oklahoma City, OK.

2002: National Award: The ACP National Scientific Research Prize: Conferred by the American College of Medicine and American Society of Internal Medicine (ACP/ASIM) at the National Annual Scientific Session, Philadelphia, PA.; The American College of Physicians

2003: National Award: The ACP National Scientific Research Prize: Conferred by the American College of Medicine and American Society of Internal Medicine (ACP/ASIM), Annual Scientific Session, San Diego, CA.; The American College of Physicians/American Society of Internal Medicine

2004: T. Franklin Williams Scholars Award: Awarded for work on Aging, Glutathione Synthesis and Oxidative Stress.; Association of Subspecialty Professors (ASP) and the American Geriatrics Society (AGS)

2009: Fulbright and Jaworski LLP Award: Awarded for for excellence in education in the category of ‘teaching and evaluation’; ��vlog�� of Medicine

2011: Fulbright and Jaworski LLP Award: Awarded for excellence in education in the category of ‘development of enduring educational materials’; ��vlog�� of Medicine

2012: International Award for Publishing Excellence: Conferred for manuscript published in the Journal of Clinical Endocrinology and Metabolism; Endocrine Society

2013: Special Invited Presentation to the 41st President of the United States: Personal invitation from the 41st President of the United States, Mr. George H. W. Bush for a private presentation and discussion of my research on “The Role of GlyNAC in Aging”, which took place in his office on November 17, 2013.

2017: Star Clinician Award: Awarded for for Excellence in Patient Care; ��vlog�� of Medicine

2018: Second Place Award, Clinical Research Category (Mentor): Annual Medicine Research Symposium, ��vlog�� of Medicine, Houston, TX, USA; ��vlog�� of Medicine

2019: First Place Award, Clinical Research Category (Mentor): Awarded at the Annual Medicine Research Symposium, ��vlog�� of Medicine, Houston, TX, USA; ��vlog�� of Medicine

2019: Second Place Award, Basic Science Research Category (Mentor): Awarded at the Annual Medicine Research Symposium, ��vlog�� of Medicine, Houston, TX, USA; ��vlog�� of Medicine

2020: Editor's Choice paper: Published manuscript selected as 'Editor's Choice' paper: https://www.mdpi.com/2227-9059/8/10/390; Journal 'Biomedicines'

2023: Editor's Choice paper: Manuscript selected as 'Editor's Choice' article. https://doi.org/10.1093/gerona/glac135; Journal of Gerontology - Medical Sciences (01/2023)

Professional Interests

Resarch: Understanding and reversing defects in nutrient, mitochondrial and energy metabolism to improve health
Resarch: Developing novel strategies to promote healthy aging
Resarch: Improving brain health and reversing cognitive decline
Resarch: Novel approaches in diabetes
Resarch: Metabolic and cognitive disorders in HIV-infection and infectious disease
Educational intests: Being an educator at all levels, while also being a learner. Special focus on simplifying concepts about disease for patients, as in the ABCDE approach for diabetes.
Clinical interests: General Endocrinology, Diabetes, and Metabolic disorders

Professional Statement

Research: to explore, investigate, evaluate and understand the basis of illness and disease in terms of redox imbalance, mitochondrial impairment and glutathione deficiency, and to identify novel solutions to improve health and longevity.
Educational: to teach at all levels, and simplify concepts to facilitate understanding.
Clinical: to provide the best care to patients with endocrine and metabolic disorders.

Websites

Section of Endocrinology, Diabetes and Metabolism

Selected Publications

Nguyen D, Samson SL, Reddy VT, Gonzalez EV, Sekhar RV. " " Aging Cell. 2013 Jun ; 12 (3) : 415-25.
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Sekhar RV, McKay SV, Patel SG, Guthikonda AP, Reddy VT, Balasubramanyam A, Jahoor F. " " Diabetes Care. 2011 Jan ; 34 (1) : 162-7.
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Kumar P, Osahon OW, Sekhar RV.. " " Nutrients. 2022 Mar ; 14(5):1114
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Sekhar RV. " " Antioxidants. 2022 Jan ; 13;11(1):154
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Kumar P, Osahon O, Vides DB, Hanania N, Minard CG, Sekhar RV. " " Antioxidants. 2021 Dec ; 11(1):50
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Sekhar RV. " " Journal of Nutrition. 2021 Dec ; 151 (12) : 3606-3616.
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Sekhar RV. " " AIDS. 2021 Jul 15; 35 (9) : 1522-1524.
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Kumar P, Liu C, Hsu JW, Chacko S, Minard C, Jahoor F, Sekhar RV. " " Clinical and Translational Medicine. 2021 Mar ; 11(3):e372
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Kumar P, Liu C, Suliburk JW, Minard CG, Muthupillai R, Chacko S, Hsu JW, Jahoor F, Sekhar RV. " " Biomedicines. 2020 Sep ; 8(10):390
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Cieslik KA, Sekhar RV, Granillo A, Reddy A, Medrano G, Heredia CP, Entman ML, Hamilton DJ, Li S, Reineke E, Gupte AA, Zhang A, Taffet GE. " " J Gerontol A Biol Sci Med Sci. 2018 Aug 10; 73 (9) : 1167-77.
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Sekhar RV et al. " " AIDS. 2015 Sep 10; 29 (14) : 1899-1900.
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Nguyen D, Hsu JW, Jahoor F, Sekhar RV. " " J Clin Endoc Metab. 2014 Jan ; 99(1):169-77
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Sekhar RV et al. " " Am J Clin Nutrition. 2011 Sep ; 94(3):847-53
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Kumar P, Liu C, Suliburk J, Hsu JW, Muthupillai R, Jahoor F, Minard C, Taffet GE, Sekhar RV. " " J Gerontol A Biol Sci Med Sci. 2023 Jan 26; (78(1)) : 75-89.
Pubmed PMID: .
Kumar P, Osahon OW, Sekhar RV. " " Antioxidants. 2023 May ;

Projects

Randomised Clinical Trial of GlyNAC supplementation in Mild Cognitive Impairment (MCI)
Randomized Clinical Trial of GlyNAC supplementation in Alzheimer's disease
Translational studies in basic sciences and clinical trials in: Aging, Premature-Aging, Cognitive decline, Diabetes, HIV-aging, Disorders of energy metabolism
Randomized Clinical Trial of GlyNAC supplementation in Older Adults: completed and published (https://doi.org/10.1093/gerona/glac135)

Memberships

American Aging Association

Gerontological Society of America

Funding

R01 funding: National Institutes of Health

Skills

Endocrine disorders

Diabetes and Insulin resistance

Energy, mitochondrial and nutrient metabolism

Age-associated cognitive decline

Glutathione biology and Oxidative Stress

HIV-associated metabolic disease

Analogy-based comprehensive diabetes education (ABCDE)

GlyNAC supplementation in aging, cognitive decline, HIV-infection and Diabetes

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