ÌÇÐÄvlogÃÛÌÒ

Sebastian Acosta

Acosta

Sebastian Acosta, Ph.D.

Assistant Professor

Positions

Assistant Professor
Pediatrics - Critical Care
Analytics Laboratory
ÌÇÐÄvlogÃÛÌÒ of Medicine
Houston, TX, US

Education

PhD from Rice University
05/2014 - Houston, Texas, United States
Computational and Applied Mathematics, Biomechanics and Inverse Problems
MS from Brigham Young University
05/2011 - Provo, Utah, United States
Mathematics, Partial Differential Equations
BS from Brigham Young University
05/2009 - Provo, Utah, United States
Mechanical Engineering, Fluid Dynamics

Honors & Awards

AMS-Simons Travel Grant 2015-2017
BP Scholarship Award in Science 2012
Selected Participant SIAM Summer School on Waves and Imaging 2011
Graduate Research Award BYU Math 2011
Graduate Research Fellowship BYU Math 2010
Orson Pratt Prize for most outstanding graduating senior, BYU Math 2009
Brigham Young Bicentennial Scholar
World Young Researchers for the Environment WYRE 2000
NSF-DMS Grant
(07/2017 - 06/2020)
NIH-NIBIB grant

Professional Interests

  • Computational Biomechanics
  • Inverse Problems and Imaging
  • Machine Learning, predictive analytics for critical care

Professional Statement

Advanced computational methods and artificial intelligence are becoming a promising factor to improve the assessment and treatment of pathological conditions. My goal is to further this line of scientific endeavor and reinforce the translation of quantitative methods into clinical practice. I am an interdisciplinary scientist who works at the interface between mathematics, statistics, engineering and medicine. My areas of expertise are biomechanics, computational science, and mathematical and statistical methods of inference. Current applications include predictive analytics for the deterioration of ICU patients, for hemodynamic irregularities, improving quality and automation of ultrasound-based imaging, photoacoustic imaging, decision-making, and planning/scheduling optimization.

Websites

Selected Publications

  • S. Acosta, D. Penny, C. Rusin. " " Microvasc. Res.. 2015 ; 100 : 40-47.
  • S. Acosta and C. Montalto. " " Inverse Problems. 2015 ; 31 : 065009.
  • S. Acosta, C. Puelz, B. Riviere, D. Penny, C. Rusin. " " J. COmput. Phys.. 2015 ; 294 : 96-109.
  • S. Acosta. " " Inverse Prob & Imaging. 2015 ; 9 : 301-315.

Memberships

AHA: American Heart Association
SIAM: Society for Industrial and Applied Mathematics
US Association for Computational Mechanics

Funding

Collaborative Research: Improved Algorithms for Multiwave Imaging in Complex Media: Theory and Computation
#1712725
(07/15/2017 - 06/30/2020)
Grant funding from NSF-DMS
Novel pseudo-differential methods to drastically increase computational speed and accuracy for biomedical ultrasound imaging and focusing
#1R15EB035359-01A1
Grant funding from NIH
The PreVAIL-kIds Common Protocol
#4R33HD105593
Grant funding from NIH

Intellectual Property

Method of predicting fluid responsiveness in patients
Method Patent #11504015 (Approved)
A technique for predicting fluid responsiveness in a critically ill patient comprises measuring physiological data of the patient, then generating an estimate of pulse pressure vari ability from a Fourier transform of the physiological wave form. Both invasive and non-invasive physiological data measurements may be used.
Co Inventors: Sebastian Acosta, Mubbasheer Ahmed, Suellen Yin, Kenneth M Brady, Daniel J Penny, Craig Rusin
Clinical metric for predicting onset of cardiorespiratory deterioration in patients
Method Patent #10485486 (Approved)
A system generates and displays a clinical metric based on continuously collected patient physiological data, wherein the clinical metric provides a predictive measure of the likelihood of the onset of a cardiorespiratory deterioration event in the patient in a predetermined time period in the future. If the clinical metric has a configured relationship with a predetermined threshold value, embodiments may generate an alarm in addition to or instead of displaying the clinical metric. The clinical metric thus allows clinical staff to take medically indicated actions to prevent or reduce the effects of the predicted deterioration.
Co Inventors: Craig Rusin, Kenneth M Brady, Eric Vu, Sebastian Acosta, Daniel J Penny

Languages

Spanish

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