Shixia Huang

Shixia Huang, Ph.D.

Professor

Email

shixiah@bcm.edu

Positions

Professor: Mol & Cell Biology
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Director, Antibody-Based Proteomics Core: Advanced Technology Cores
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Houston, Texas, United States

Professor: Education, Innovation & Technology
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Faculty Senator: ��vlog�� of Medicine

Member: Dan L Duncan Comprehensive Cancer Center
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Program Director, BRITE: ��vlog�� of Medicine
Biotechnology Research Incubator for Teachers (BRITE) www.bcm.edu/BRITE

Education

PhD from Michigan State University: East Lansing, Michigan, United States; Genetics

Postdoctoral Fellowship at National Cancer Institute: Bethesda, Maryland, United States

Postdoctoral Fellowship at Memorial Sloan-Kettering Cancer Center: New York, New York, United States

MS from Yangzhou University: Yangzhou, Jiangsu, China, People's Rep; Infectious Disease & Preventive Veterinary Medicine

BS from Hunan Agricultural University: Changsha, Hunan, China, People's Rep; Veterinary Medicine

Professional Statement

Developing high-throughput antibody-based proteomic platforms for protein biomarker discovery and validation, especially for low abundance regulatory proteins and their activation states such as phosphorylation and histone translational modifications.
Combining my advanced technology expertise and passion for education to build biotechnology research education programs.

Websites

Antibody-based Proteomics Core

The Antibody-based Proteomics Core provides cutting-edge antibody-based proteomic platforms for both validation and protein biomarker discovery, particularly for low abundance regulatory proteins and activation states of proteins with phosphorylated antibodies.

Leveraging ��vlog�� of Medicine's advanced technology and cancer research resources, the Biotechnology Research Education Programs include NIH-funded training programs for teachers and college students, as well as internally funded programs for high school students by the Lester and Sue Smith Center.

Selected Publications

Huang S, Li Y, Chen Y, Podsypanina K, Chamorro M, Olshen AB, Desai KV, Tann A, Petersen D, Green JE, Varmus HE. " " Genome Biol.. 2005 ; 6 (10) : R84.
Pubmed PMID: .
Huang S, Flanders KC, Roberts AB. " " Gene. 2000 Nov 27; 258 (41276) : 43-53.
Pubmed PMID: .
Li Y, Welm B, Podsypanina K, Huang S, Chamorro M, Zhang X, Rowlands T, Egeblad M, Cowin P, Werb Z, Tan LK, Rosen JM, Varmus HE. " " Proc. Natl. Acad. Sci. U.S.A.. 2003 Dec 23; 100 (26) : 15853-8.
Pubmed PMID: .
Lu, H.-Y., Xiong, j., Perera, D. N., Rajapakshe, K., Wang, X., Costello M., Holloway K. R., Ramos, C., Grimm, S. L., Wulfkuhle, J., Coarfa, C., Edwards, D. P., Zhu, M. X., and Huang, S.. " High-throughput Evaluation of Metabolic Activities Using Reverse Phase Protein Array (RPPA) Technology. " Book chapter in: Tong, Q., 1st ed. Neuronal Signaling in Metabolism. 2021 Jun ; 1st Edition : 25.
Coarfa C, Grimm SL, Rajapakshe K, Perera D, Lu HY, Wang X, Christensen KR, Mo Q, Edwards DP, Huang S.. " " J Biomol Tech.. 2021 Apr ; 32 (1) : 15-29.
Pubmed PMID: .
Dong J, Huang S, Caikovski M, Ji S, McGrath A, Custorio MG, Creighton CJ, Maliakkal P, Bogoslovskaia E, Du Z, Zhang X, Lewis MT, Sablitzky F, Brisken C, Li Y. " " Development. 2011 Dec ; 138 (23) : 5247-56.
Pubmed PMID: .
Huang S, Chen Y, Podsypanina K, Li Y. " " Neoplasia. 2008 Feb ; 10 (2) : 118-24.
Pubmed PMID: .
Huang S, Tang B, Usoskin D, Lechleider RJ, Jamin SP, Li C, Anzano MA, Ebendal T, Deng C, Roberts AB. " " Genesis. 2002 Feb ; 32 (2) : 76-9.
Pubmed PMID: .

Memberships

Human Proteome Organization: Education and Training Committee (03/2023)

Association of Biomolecular Resource Facilities (ABRF): Education Committee (03/2021)

Funding

Biotechnology Research Incubator for Teachers (BRITE): $1,250,000.00 (07/01/2024 - 04/30/2029); NIH R25 Science Educatin Partnership Award (SEPA); The Biotechnology Research Incubator for Teachers (BRITE) program provides middle school teachers in the Houston area with summer research opportunities, aligning with Next Generation Science Standards and bridging the gap between research experiences, AI guided literature adaptation,, and classroom instruction. BRITE aims to enhance science education, empower teachers, and inspire students to pursue STEMM fields.

Cancer Research Education Program (C-REP) for NIH P20 BCM/TSU CURED: (09/21/2023 - 08/31/2027); NIH P20 C-REP; The Collaborative Cancer Research Education Program (C-REP) of the ��vlog�� of Medicine (BCM)/ Dan L Duncan Comprehensive Cancer Center (DLDCCC) and Texas Southern University (TSU) P20 Collaborative Union for Cancer Research, Education and Disparities (CURED) project will train 20 TSU underrepresented minority students in cancer research, cutting edge technologies, and career pathway. The cohort of 20 CURED scholars will participate in an 8-week mentored cancer research experience that integrates BCM and TSU infrastructures every summer followed by year-long culturally congruent outreach education activities that will increase the awareness, knowledge, and understanding of research, concepts, processes, and careers in cancer research/cancer health disparities.

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