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The Roy M. and Phyllis Gough Huffington Center on Aging spearheads breakthrough research and is committed to translating basic research discoveries into applications that promote healthy aging and combat age-associated disorders. The faculty, along with their research staff and trainees, utilize diverse model systems and multidisciplinary approaches to address questions that are of crucial importance to the biology, pathophysiology and diseases of aging. The major research topics include lifespan and health span studies, aging of the endocrine, vasculature, and central nervous systems, cancer, and neurodegenerative diseases, in particular Alzheimer’s disease. Through close alignment with the Division of Geriatrics and Palliative Medicine in the Department of Medicine, the HCOA also provide medical education and training and deliver healthcare  through affiliated hospitals.

The HCOA was formed in 1988 by the generosity of the late Roy M. and Phyllis Gough Huffington, Houston philanthropists who foresaw the need for an academic entity devoted to studying aging, providing care for older people, and teaching future health professionals and researchers about geriatrics and gerontology.